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      crossover
      相關語句
        交叉
          A OUASILINEAR MODEL FOR ANALYSING DATA OF CROSSOVER TRIALS
          交叉試驗設計分析的擬線性模型
      短句來源
          Methods:Twenty male healthy volunteers received 2mg finasteride tablet orally in a random crossover design.
          方法采用隨機雙交叉實驗設計,20名健康受試者口服受試制劑和參比制劑2mg,用LC-MS法測定國人血漿中的非那雄胺濃度。
      短句來源
          METHODS: The study was conducted as a 3- way crossover design in 18 healthy volunteers whose plasma concentrations of cefixime were determined by HPLC after receiving a single oral dose of 200 mg trial preparations or reference preparation.
          方法:采用高效液相色譜法測定18名健康受試者三交叉單劑量口服受試制劑或參比制劑200mg后血漿中頭孢克肟的濃度。
      短句來源
          Methods Twenty healthy male volunteers received 200 mg nevirapine tablets orally in a random crossover design. Drug concentrations in the plasma were determined by HPLC.
          方法采用隨機雙交叉實驗設計,20名健康受試者口服受試制劑和參比制劑200 mg,用HPLC法測定血漿中的奈韋拉平濃度。
      短句來源
          Methods A single oral dose (100 mg of tested and reference formulation) were given to 20 healthy volunteers in a randomised crossover study.
          方法健康志愿者20名,隨機雙交叉單劑量口服鹽酸舍曲林分散片和片劑100mg,分別于服藥后120h內多點抽取靜脈血;
      短句來源
      更多       
        交叉
          A OUASILINEAR MODEL FOR ANALYSING DATA OF CROSSOVER TRIALS
          交叉試驗設計分析的擬線性模型
      短句來源
          Methods:Twenty male healthy volunteers received 2mg finasteride tablet orally in a random crossover design.
          方法采用隨機雙交叉實驗設計,20名健康受試者口服受試制劑和參比制劑2mg,用LC-MS法測定國人血漿中的非那雄胺濃度。
      短句來源
          METHODS: The study was conducted as a 3- way crossover design in 18 healthy volunteers whose plasma concentrations of cefixime were determined by HPLC after receiving a single oral dose of 200 mg trial preparations or reference preparation.
          方法:采用高效液相色譜法測定18名健康受試者三交叉單劑量口服受試制劑或參比制劑200mg后血漿中頭孢克肟的濃度。
      短句來源
          Methods Twenty healthy male volunteers received 200 mg nevirapine tablets orally in a random crossover design. Drug concentrations in the plasma were determined by HPLC.
          方法采用隨機雙交叉實驗設計,20名健康受試者口服受試制劑和參比制劑200 mg,用HPLC法測定血漿中的奈韋拉平濃度。
      短句來源
          Methods A single oral dose (100 mg of tested and reference formulation) were given to 20 healthy volunteers in a randomised crossover study.
          方法健康志愿者20名,隨機雙交叉單劑量口服鹽酸舍曲林分散片和片劑100mg,分別于服藥后120h內多點抽取靜脈血;
      短句來源
      更多       
        “crossover”譯為未確定詞的雙語例句
          METHODS Sixteen healthy volunteers were given medicine 60mg in oral by an open randomized crossover design.
          方法:健康志愿者16名隨機交叉口服給藥60mg。
          marketedcapsule and marketed injection in a randomized crossover way. A two-compartment open model was adopted. Calculated areas under curve(AUC) were 2105 ug/ml-min 1344.31 ug/ml*min and 1456.7ug/ml*min with respective of sustained-release tablet (300mg).
          動力學特征符合二室模型,普通膠囊(300mg)和緩釋片(300mg)的曲線下面積(AUC)分別為1344.31ug/ml~*min和2105ug/ml~*min;
      短句來源
          The pharmacokinetics of Germanium was determined following a single oral dose of 200 mg given to each 10 volunteers in an open randomized crossover study The peak levels in serum averaged 8544±3019 ng/ml at 244 ±037 h;
          10名健康志愿者口服單劑量(200mg)有機鍺膠囊,測得血清中藥物濃度在2.44±0.37h達到峰值854.4±301.9ng/ml。
      短句來源
          Following oral administrations of a single dose of 150 mg roxithromycin dispersible tablet (formulation A, a new formulation for clinical trial) and conventional tablet (formulation B, purchased from the market) to each of 10 healthy male volunteers in a randomized crossover design, the plasma levels of active drug at different times were determined by a microbial assay with Micrococcus luteus CMCC (B) 28001 and the plasma concentration—time profiles were obtained.
          為比較不同劑型羅紅霉素的生物利用度,用微生物管碟檢定法(藤黃微球菌CMCC(B)28001)測定了10名男性健康受試者口服羅紅霉素分散片(制劑A)和羅紅霉素片(制劑B)后不同時間血漿中活性藥物的濃度,繪制了血藥濃度—時間曲線。
      短句來源
          A single oral dose containing 480 mg of rifampicin (RFP), 1000 mg of pyrazinamid (PZA) and 320 mg of isoniazid (INH) was given to 12 volunteers in an randomized crossover study .
          單劑量口服(內含利福平(RFP)480mg,吡嗪酰胺(PZA)1000mg,異煙肼(INH)320mg)參比藥進口異福酰胺和國產試驗藥各4片 ,對國產復方利福平片與進口異福酰胺作人體生物利用度比較。
      短句來源
      更多       
      查詢“crossover”譯詞為用戶自定義的雙語例句

          我想查看譯文中含有:的雙語例句
      例句
      為了更好的幫助您理解掌握查詢詞或其譯詞在地道英語中的實際用法,我們為您準備了出自英文原文的大量英語例句,供您參考。
        crossover
      At each iterate, by reduplication, crossover and mutation, a finite set of points can be used.
            
      For the genetics algorithm, chromosome coding, fitness function, parameters selection, and the basic genetics operation including selection, crossover and aberrance, are described.
            
      Eight young, healthy male volunteers were exposed to two 24 h periods of continuous wakefulness during the crossover experiment.
            
      Numerical investigation of aerodynamic performance influenced by circumferentially pre-swirling coming flow on the crossover and
            
      Numerical investigation is implemented on aerodynamic performance inside the crossover and de-swirling cascade of a multistage centrifugal compressor.
            
      更多          


      The in vitro dissolution rates from 5mg prednisolone tablets anddropped pills were determined using de-ionized water as the dissolutionmedium. A three crossover bioavailability study was performed in 8 humanadult volunteers comparing the fastest-and slowest-dissolving brand anddropped pills. The plasma samples were assayed for prednisolone by acompetitive protein binding method. The mathematical two-compartmentmodel(oral) by digital computer program and statistical analysis of thedata for two brand tablets...

      The in vitro dissolution rates from 5mg prednisolone tablets anddropped pills were determined using de-ionized water as the dissolutionmedium. A three crossover bioavailability study was performed in 8 humanadult volunteers comparing the fastest-and slowest-dissolving brand anddropped pills. The plasma samples were assayed for prednisolone by acompetitive protein binding method. The mathematical two-compartmentmodel(oral) by digital computer program and statistical analysis of thedata for two brand tablets showed significant differences between Cm.Tm.and Auc. of prednisolone samples. The dropped pills were essentiallyequivalent to the fastest tablet, but its potency was two times as highas the slowest one. The in vitro dissolution was correlated with thesein vivo results. The results of calculation on the two-compartment model show thatthe values of α and β are different from each other. A value becomes large,and the rate constant K_1, K_2, KE all positive It may be presumed thatprednisolone belongs to a two-compartment drug.

      本研究系從體外試驗中選擇了溶解速度最快和最慢的二個不同廠的片劑與滴丸進行體內有效性試驗。采用競爭性蛋白結合法測定血中強的松龍濃度。經兩室模型(口服)的數學處理和電子計算機運算結果表明在兩種片劑之間有顯著差異。滴丸與片劑(A)是等效的,但倍效于片劑(C)。體外一體內存在相關關系。α與β值相差較大,A值也大,速度常數K_1、K_2、K_E均為正值,可以認為強的松龍屬兩室模型藥物。

      The study was carried out in a test group of six partially gastrotomized human volunteers by the urinary excretion method and results obtained were compared with a control group of nine healthy human volunteers. Both groups received three riboflavin solid dosage forms with two different dosage regimens in a crossover design. The observed data were fitted to a two compartment model by using the PKP Ⅱ (2) digital computer program on a microcomputer for both dosage regimens for each subject.A significant...

      The study was carried out in a test group of six partially gastrotomized human volunteers by the urinary excretion method and results obtained were compared with a control group of nine healthy human volunteers. Both groups received three riboflavin solid dosage forms with two different dosage regimens in a crossover design. The observed data were fitted to a two compartment model by using the PKP Ⅱ (2) digital computer program on a microcomputer for both dosage regimens for each subject.A significant difference in the amount of excretion of riboflavin was found between the two groups, urinary recovery of riboflavin was lower in the test group than in the control group (P<0.01). In comparing the pharmacokinetic parameters, Ka was significantly greater and Tmax was significantly less in the test group than in the control group, but no statistically significant difference in the values of β was observed.These differences are attributed to gastric emptying rates as well as the dissolution rates of the dosage forms.These results suggest that it is practically possible to increase the bioavailability of persons after partial gastroctomy by administering rapid release preparations or by multiple dosage regimen,

      以胃大部切除術(Billroth Ⅰ式)后已恢復健康的人為對象,研究核黃素的不同劑型、不同給藥方法的生物利用度及動力學參數,將結果與正常人對比(對照組),探討提高生物利用度的方法。數據處理按PKPⅡ(2)程序在微型計算機上進行。結果表明,胃大部切除者的核黃素口服吸收率低于正常人,而吸收速度大于正常人,動力學參數Ka、Tmax在胃切除組與對照組間可有非常顯著或顯著的差異,而β無顯著差異。作者認為提高胃大部切除者的核黃素生物利用度,可通過制成釋放速度較快的制劑或采用小劑量多次給藥的方案來實現。

      In order to avoid high initial peak of the commercially available indomethacin formulation and increase the interval between dosages, comparison of three sustained release indomethacin capsules on pellet coated with Eudragit-E_((?)0)D and a commercially available tablet was carried out by testing in vitro the dissolution behaviour and in vivo bioavailability. Dissolution studies on three batches of pellet capsules with varying drug to coat material ratios (mg/cm~2) exhibited a sustained release pattern. In vivo...

      In order to avoid high initial peak of the commercially available indomethacin formulation and increase the interval between dosages, comparison of three sustained release indomethacin capsules on pellet coated with Eudragit-E_((?)0)D and a commercially available tablet was carried out by testing in vitro the dissolution behaviour and in vivo bioavailability. Dissolution studies on three batches of pellet capsules with varying drug to coat material ratios (mg/cm~2) exhibited a sustained release pattern. In vivo serum level for 8 adult male subjects of randomized crossover design showed no statistical difference in bioavailability between different capsule formulations and a tablet formulation available on the market. However, these three capsule formulations demonstrated a higher and smoother serum concentrationtime curves than that of the tablet formulation from 4 to 12 h following a single dose(50mg). The serum level of three capsule formulations was significantly higher than that of the tablet formulation (P<0.1) at the 12th h respectively. In vitro dissolution behaviour and in vivo bioavailability, the linear relationships were found between T_(50) or T_(m(?)x) and drug to coat material ratios.

      消炎痛普通制劑口服吸收迅速,可出現不必要的高血藥濃度,導致不良反應。為此我們對三種消炎痛緩釋膠囊(A,B,C)和一種常用片劑(D)作了體外溶出試驗和體內生物利用度比較。膠囊制劑由丙烯酸類樹脂材料E_(30)D包衣的藥物小丸制成,其體外溶出行為顯示緩慢釋放圖象。在8名成年男性交叉實驗中,不同膠囊制劑和普通片劑之間的Tmax,Cmax和AUC_(0~124)經方差分析無統計學差異,但是在給藥后4至12小時的血清濃度—時間曲線,均比普通片劑高而平滑。在第12小時,三種膠囊產生的血清濃度顯著高于普通片劑(P<0.1)。根據體外溶出行為和體內生物利用度發現T_(50)或Tmax和包衣厚度呈良好線性關系。

       
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