1. 
      

    2. <ol id="72tk1"><tbody id="72tk1"></tbody></ol>
    3. 助手標題  
      全文文獻 工具書 數字 學術定義 翻譯助手 學術趨勢 更多
      查詢幫助
      意見反饋
         bioequivalence 在 藥學 分類中 的翻譯結果: 查詢用時:0.009秒
      圖標索引 在分類學科中查詢
      所有學科
      藥學
      有機化工
      中藥學
      醫藥衛生方針政策與法律法規研究
      計算機軟件及計算機應用
      基礎醫學
      生物醫學工程
      數學
      臨床醫學
      更多類別查詢

      圖標索引 歷史查詢
       

      bioequivalence
      相關語句
        生物等效性
          Development of LDP Sustained-release Tablets and Evaluation of Bioequivalence
          LDP緩釋片的研制及生物等效性評價
      短句來源
          Relative Bioavailability and Bioequivalence Assessment of Domestic Amiloride Tablet
          國產氨氯吡咪片的相對生物利用度及其生物等效性評價
      短句來源
          THE APPLICATION OF MIC RELATED PARAMETERS IN THE BIOEQUIVALENCE TEST OFCEFADROXIL GRANULES
          MIC關聯的參數在頭孢羥氨芐顆粒劑生物等效性試驗中的應用
      短句來源
          Studies on Bioequivalence of Domestic and Imported Tablets of Ibuprofen
          國產與進口布洛芬糖衣片生物等效性研究
      短句來源
          Objective To study the relative bioavailability and bioequivalence of compound glipizide in healthy volunteers.
          目的研究復方格列吡嗪片人體生物利用度及生物等效性
      短句來源
      更多       
        “bioequivalence”譯為未確定詞的雙語例句
          OBJECTIVE To evaluate the bioequivalence of domestic tropisetron preparations and imported tablets.
          目的評價國產鹽酸托烷司瓊片、膠囊與進口參比制劑是否生物等效。
      短句來源
          the pharmacokinetic parameters and relative bioavailability were calculated and the bioequivalence of the 2 preparations were evaluated. Results: The pharmacokinetic parameters for experimental and the reference preparations were: C_max(6.21±1.88) vs(6.03±1.08) ng/ml; AUC_0-120(250.68±52.61) vs(246.14±52.11) ng h/ml;
          結果:苯磺酸氨氯地平供試制劑和參比制劑主要藥代動力學參數如下:Cmax分別為(6.21±1.88)(、6.03±1.08)ng/ml,AUC0-120分別為(250.68±52.61)、(246.14±52.11)ng.
      短句來源
          The relative bioequivalence of the test preparation was(97±12)%.
          t_(1\2β)分別為(1.9±2.3)h和(1.9±1.5)h,2種制劑的主要藥動學參數無顯著差異(P>0.05),受試制劑的相對生物利用度為(97±12)%。
      短句來源
          The concentrations of ciprofloxacin in serum samples were determined by RP-HPLC, and the bioequivalence were evaluated. RESULTS: The main pharmacokinetic parameters of the test and reference in volunteers were as follows, AUC0-t were 10.889±1.385 μ g ·h ·ml-1 and 12.406±1.384 μ g ·h ·ml-1;
          結果單劑口服給藥試驗制劑和參比制劑環丙沙星時間-濃度曲線下面積(AUC0-t)分別為10.889±1.385 μg ·h·ml-1和12.406±1.384 μg ·h ·ml-1;
          Comparative study on bioavailability and bioequivalence of clarithromycin disperse tablets andlimaixian tablets in healthy volunteers
          克拉霉素分散片與克拉霉素片人體生物利用度比較研究
      短句來源
      更多       
      查詢“bioequivalence”譯詞為用戶自定義的雙語例句

          我想查看譯文中含有:的雙語例句
      例句
      為了更好的幫助您理解掌握查詢詞或其譯詞在地道英語中的實際用法,我們為您準備了出自英文原文的大量英語例句,供您參考。
        bioequivalence
      The method was successfully applied to investigate the bioequivalence between two kinds of tablets (test versus reference products) in 18 healthy male Chinese volunteers.
            
      Bioanalytical laboratories support a range of regulatory studies ranging from early toxicology studies through Phase 1,2 and 3 clinical studies to definitive bioequivalence and bioavailabity studies in support of the marketed product.
            
      With a total run-time of 6 minutes, the method was suitable for supporting clinical studies and applied to the analysis of samples from a bioequivalence study.
            
      A new sensitive HPLC-FLD method has been developed and validated for the determination of cisapride in human plasma for a bioequivalence study.
            
      This method has been successfully used to support a bioequivalence clinical study.
            
      更多          


      This paper deals with the formulation, preparation and evaluation of sustained-release theophylline tablet (SRTT) by measuring in vitro/in vivo release. The serum levels of theophylline in 12 healthy adult volunteers after oral administration of SRTT were determined by a modified UV spectrophotometric method. The pharmac0kinetic parameters were fitted by non-linear least square method with Sharp PC-1211 pocket-computer on the basis of one compartment model. The result showed that the therapeutic serum levels...

      This paper deals with the formulation, preparation and evaluation of sustained-release theophylline tablet (SRTT) by measuring in vitro/in vivo release. The serum levels of theophylline in 12 healthy adult volunteers after oral administration of SRTT were determined by a modified UV spectrophotometric method. The pharmac0kinetic parameters were fitted by non-linear least square method with Sharp PC-1211 pocket-computer on the basis of one compartment model. The result showed that the therapeutic serum levels after single dose of SRTT (300 mg) appeared at 3.8 h and maintained over 5 μg/ml for up to 23 h, while that of multiple dose of SRTT (300 mg/every 12 h)appeared at 3 h and reached steady state (13.78±0.47 μg/ml) on the third day.By comparing the pharmacokinetic parameters between SRTT and an imported sustained-release product (Theo-Dur), a good bioequivalence was demonstrated. The correlation between dissolution rates and serum levels was mathematically treated by deconvolution method, and the calculated theoretical values was consistent with the observed data.

      本文研究了長效茶堿片(SRTT)的處方組成,制備工藝,溶出速率;并應用改進的紫外分光光度法測定了l2名健康受試者口服SRTT后的體內血藥濃度,實驗數據按單室模型用電子計算機進行處理得各藥物動力學參數。SRTT單劑量給藥(300 mg),3.8小時達有效血藥濃度,可維持5μg/ml以上23小時;多劑量給藥,3小時達有效血藥濃度,至第三天已達穩態血藥濃度13.78±0.47μg/ml。將SRTT與世界名牌產品Theo-Dur進行對照試驗,表明兩制劑為生物等效。本文采用脫卷積法計算體內外相關性,理論值與實測值基本相符。

      The concentration of OFLX in urine of six heaithy volunteers was determined after the tablets of foreign product anddomestic product were orally given by single-dose.The results showed that both products had same pharmacokinetic parametersand bioequivalence.The pharmacokinetic parameters were K(hr~(-1)):0.1185;0.1180;T 1/2(hr):5.94,6.11;Xu~(0.24)(mg):174.66,167.69;and eliminative rate:87.33%,83.89%.

      本文用尿藥濃度法測定六名志愿者單劑量口服國產、進口兩種氧氟沙星片劑的尿藥濃度,結果表明:國產與進口兩種片劑具有相同的藥動學特征及生物等效性。其藥動學參數分別為:k(h~(-1)):0.1185、0.1180;T_(1/2)(h):5.94、6.11;(?)—24(mg):174.66、167.79;排泄率:87.33%、83.89%

      The concentration of isosorbide 5-minonitrate in human plasma were determined by capillary column gas-liquid chromatography. This method has high selectivity and reproducibility. The relation between hight and concentration was very good r=0.9999. The limit of detection was 0.03 ng. The average of within-day and without-day CV was<5 %.The curve of concertration-time fitted a two-compartment open model after oral dose of 1 tablet of Chinese-made and Holland-made of isosorbide 5-minonitrate (20 mg/tablet) in the...

      The concentration of isosorbide 5-minonitrate in human plasma were determined by capillary column gas-liquid chromatography. This method has high selectivity and reproducibility. The relation between hight and concentration was very good r=0.9999. The limit of detection was 0.03 ng. The average of within-day and without-day CV was<5 %.The curve of concertration-time fitted a two-compartment open model after oral dose of 1 tablet of Chinese-made and Holland-made of isosorbide 5-minonitrate (20 mg/tablet) in the healthy, The result of pharmacokinetics of them has no difference. Ka were 4. 69, 4. 91 h-1 respectively, Cmax were 225.18,222.80μg/l, T1/2βwere 5.60and 5.61; Vd were 0.063 and 0.070 L; Cls were 13.01 and 12.401/h . The bioequivalence F= 98.28 ±9.76%.

      本文報道了應用毛細管氣相色譜法以ECD(Ni-63)為檢測器,采用外標法測定人血漿中的5-單硝基異山梨醇酯(IS-5-MN).結果表明該方法精密度好,靈敏度高,線性關系良好;r=0.9999(n=6),最低檢測限為0.03ng,日內和日間平均變異系數<6%。10名健康志愿者口服國產和進口IS-5-MN片所得的藥時曲線均符合二室模型,其藥代動力學參數無顯著性差異。吸收速率常數分別為4.69,4.91h ̄-1;達峰時間為0.89,0.81h;峰濃度為225.18,222.80μg/l;半衰期T1/2β為5.60,5.61h;表觀分布容積為0.063和0.0701;平均總體清除率為13.01和12.401/h,生物利用度F=98.28±9.76%。

       
      << 更多相關文摘    
      圖標索引 相關查詢

       


       
      CNKI小工具
      在英文學術搜索中查有關bioequivalence的內容
      在知識搜索中查有關bioequivalence的內容
      在數字搜索中查有關bioequivalence的內容
      在概念知識元中查有關bioequivalence的內容
      在學術趨勢中查有關bioequivalence的內容
       
       

      CNKI主頁設CNKI翻譯助手為主頁 | 收藏CNKI翻譯助手 | 廣告服務 | 英文學術搜索
      版權圖標  2008 CNKI-中國知網
      京ICP證040431號 互聯網出版許可證 新出網證(京)字008號
      北京市公安局海淀分局 備案號:110 1081725
      版權圖標 2008中國知網(cnki) 中國學術期刊(光盤版)電子雜志社
      97伦理电影院